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Medical Applications
3D Image Overlay
X-ray vision has always been the dream of surgeons; Image Overlay is the next best thing.
ASAP
Non-contact 3-D surgical instrument tracking for device testing and surgeon assessment.
Biodegradable Electronics
We are developing implantable biodegradable electronic devices offer the potential to provide therapeutic functions for limited periods of time - weeks to months – degrading in register with the anticipated needs of the application and thus not requiring surgical removal. One application is a biodegradable radio frequency (RF) power generator connected to electrical stimulating electrodes to enhance bone regeneration.

Biologically Inspired Micro Robotics
This project seeks to develop a joint angle sensor for a robotic cricket, which is part of a larger project with Case Western Reserve University.
BioMEMS
We are developing implantable, wireless MEMs-based sensors for various applications, such as monitoring bone regeneration and left ventricular pressure, to provide timely feedback to clinicians to help make better decisions on timing of therapeutic interventions.

Bioprinting
We have designed and built inkjet-based bioprinters to controllably deposit spatial patterns of various growth factors and other signaling molecules on and in biodegradable scaffold materials to guide tissue regeneration.

Blood-Plasma Based Bioplastics
We have developed a manufacturing process to convert donated blood plasma and platelets into inexpensive, off-the-shelf bioactive plastics to enhance and accelerate tissue healing. These materials contain nature’s own mix of growth factors in highly concentrated solid to semi-solid forms that controllably elute these factors as the bioplastics degrade. This technology is currently in human clinical trials.

Cell Tracking
We are developing fully-automated computer vision-based cell tracking algorithms and a system that automatically determines the spatiotemporal history of dense populations of cells over extended period of time.
Computer Assisted Medical Instrument Navigation
We are developing a system to help clinicians to precisely navigate various catheters inside human hearts.
Dynamic Conformal Radiotherapy
Forecasting the Anterior Cruciate Ligament Rupture Patterns
Use of machine learning techniques to predict the injury pattern of the Anterior Cruciate Ligament (ACL) using non-invasive methods.
HeartLander
A miniature mobile robot for minimally invasive therapy on the beating heart through a single percutaneous incision.
Highly-Articulated Robotic Probe (HARP)
We developed and tested a prototype based on an innovative approach of a highly articulated robotic probe.
Hip Navigation System (HipNav)
Preoperative and intraoperative planning and execution system for high-precision total hip replacement.
Hip Range of Motion (HipROM)
Preoperative planning system for total hip replacement
Hot Flash Detection
Machine learning algorithms to detect hot flashes in women using physiological measures.
Knee Navigation Systems (KneeNav TKR/ACL) (KneeNav)
We are developing two CT-based surgical navigation systems for total knee replacement and ACL reconstructive surgery.
Knee Surgery Simulation
Haptic interface for simulated knee surgery and interaction with volumetric data.
LSTAT/Snake Robot
We are working with the US Army's TATRC department (Telemedicine & Advanced Technology Research Center) to integrate a snake robot into the LSTAT system.
Medical Image Registration
NREC designed and implemented a medical image registration system to accurately estimate a patient’s position for therapy.
Micron: Intelligent Microsurgical Instruments
Suppression of hand tremor to improve precision in microsurgery.
Needle Steering for Brain Surgery
We are developing high accuracy proportional steering of flexible needles for minimally invasive navigation in the brain.
Precision Freehand Sculpting (PFS)
We are developing a handheld tool to accurately cut bone for joint replacement surgery.
Real-Time Computer Vision-Based Cell Tracking
In collaboration with Intel, we are developing systems to track the spatiotemporal history of each and every cell and their progeny in stem cultures. Such systems can be used for applications ranging from basic biological discovery to QA/QC/optimization of stem cell expansion processes, i.e., processes to grow relatively small numbers of stem cells harvested from a patient into the millions of cells needed for therapeutic delivery of these cells back into the patient.

Soft Tissue Simulation for Plastic Surgery
Sonic FlashlightTM
We are developing a method of medical visualization that merges real time ultrasound images with direct human vision.
XAlign
2D/3D registration technique is used to analyze the postoperative pelvic radiographs and to measure placement of implants after total hip replacement