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Carnegie Mellon Robotics Institute

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Abstract

This paper focuses on extracting the ideal midsagittal plane (iMSP) from three-dimensional (3-D) normal and pathological neuroimages. The main challenges in this work are the structural asymmetry that may exist in pathological brains, and the anisotropic, unevenly sampled image data that is common in clinical practice. We present an edge-based, cross-correlation approach that decomposes the plane fitting problem into discovery of two-dimensional symmetry axes on each slice, followed by a robust estimation of plane parameters. The algorithm's tolerance to brain asymmetries, input image offsets and image noise is quantitatively evaluated. We find that the algorithm can extract the iMSP from input 3-D images with 1) large asymmetrical lesions; 2) arbitrary initial rotation offsets; 3) low signal-to-noise ratio or high bias field. The iMSP algorithm is compared with an approach based on maximization of mutual information registration, and is found to exhibit superior performance under adverse conditions. Finally, no statistically significant difference is found between the midsagittal plane computed by the iMSP algorithm and that estimated by two trained neuroradiologists

Notes

Associated Center(s) / Consortia: Vision and Autonomous Systems Center and Medical Robotics Technology Center

Associated Lab(s) / Group(s): Medical Robotics and Computer Assisted Surgery, Computational Symmetry, Biomedical Image Analysis

Associated Project(s): A Statistical Quantification of Human Brain Asymmetry and Evaluation of MSP Extraction Algorithms

Text Reference

Yanxi Liu, Robert Collins, and William E. Rothfus, "Robust Midsagittal Plane Extraction from Normal and Pathological 3D Neuroradiology Images," IEEE Transactions on Medical Imaging, Vol. 20, No. 3, March, 2001, pp. 175 - 192.

BibTeX Reference

@article{Liu_2001_3743,
   author = "Yanxi Liu and Robert Collins and William E. Rothfus",
   title = "Robust Midsagittal Plane Extraction from Normal and Pathological 3D Neuroradiology Images",
   journal = "IEEE Transactions on Medical Imaging",
   pages = "175 - 192",
   month = "March",
   year = "2001",
   volume = "20",
   number = "3",
}

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