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Lee Weiss
Research Professor

Associated centers: MRTC and CFR

Email address: lew@cs.cmu.edu

Mailing address:
MRT Center
The Robotics Institute
Carnegie Mellon University
5000 Forbes Avenue
Pittsburgh PA 15213-3890
(412) 268 6553 (Jim Osborn, Executive Director)
(412) 268 6436 (FAX)

For more information, see my personal homepage.

Jump to: Research interests | Keywords | Projects | Publications

My current research includes three bio-related focus areas: 1) Tissue Engineering, 2) MEMS sensors, and 3) Computer-Aided Surgery. To effectively carry out this research, I work with multidisciplinary teams from The School of Computer Science (Robotics), The College of Engineering, and The Mellon College of Sciences.

My research in tissue engineering involves the development of CAD/CAM systems that can fabricate biologically-inspired biomimetic scaffolds with 3D spatial patterns of growth factors, with a focus on bone regeneration.

My research in MEMS involves the development of 1) biological and chemical sensors to detect environmental toxins, and 2) implantable telemetry-based sensors for assessing tissue regeneration.

My research in computer-assisted surgery (CAS) involves the development of cost-effective, easy-to-use CAS systems for orthopedic applications.

medical robotics, MEMS, quality-of-life technology, rapid prototyping, and tissue engineering

• Cell Tracking - We are developing fully-automated computer vision-based cell tracking algorithms and a system that automatically determines the spatiotemporal history of dense populations of cells over extended period of time.
• Quality of Life Technology Center - QoLT is a unique partnership between Carnegie Mellon and the University of Pittsburgh that brings together a cross-disciplinary team of technologists, clinicians, industry partners, end users, and other stakeholders to create revolutionary technologies that will improve and sustain the quality of life for all people.

• Rapid Design and Manufacture of Wearable Computers
  S. Finger, M. Terk, E. Subrahmanian, C. Kasabach, F.B. Prinz, D. Siewiorek, A. Smailagic, J. Stivorek, and L. Weiss
  Communications of the ACM, Vol. 39, No. 2, February, 1996.

• Automated Fabrication of Complex Molded Parts Using Mold SDM
  A.G. Cooper, S. Kang, J.W. Kietzman, F.B. Prinz, J.L. Lombardi, and L. Weiss
  Materials and Design, Vol. 20, No. 2/3, June, 1998, pp. 83 - 89.

• Solid Freeform Fabrication of Scaffolds for Tissue Engineering
  L. Weiss
  Science & Medicine, 2001.

• Solid Freeform Fabrication: A New Manufacturing Paradigm
  R.H. Crawford, J.J. Beaman, C. Cavello, J.D. Jackson, L. Weiss, and C.H. Séquin
  IEEE Spectrum, Vol. 36, No. 2, 1999, pp. 34 - 43.

• Processes overview
  L. Weiss
  JTEC/WTEC panel report on rapid prototyping in Europe and Japan, Vol. 1, 1997.

• Microfabricated Probes Can be Used to Administer Gene Therapy
  M.D. Feldman, B. Sun, B.J. Koci, C. Wu, S.L. Castilla, A. Nadeem, L. Weiss, M.L. Reed, A.J.C. Smith, and W. Rosenblum
  American Journal of Cardiology, No. 82(7A), 1998, pp. 28S - 29S.

• Characterization of osteoblast-like behavior of cultured bone marrow stromal cells on various polymer surfaces
  J.W. Calvert, K.G. Marra, L. Cook, P.N. Kumta, P.A. DiMilla, and L. Weiss
  J. Biomed. Mat. Res., Vol. 52, No. 2, 2000, pp. 279 - 284.

• Microfabricated Device for Intravascular Delivery
  M. Feldman, J. Kneller, C. Wu, S. Watkins, L. Weiss, and M.L. Reed
  Journal OfThe American College Of Cardiology, No. 31(2), February, 1998, pp. 351A - 351A.

• Process Methods
  J. Beaman and L. Weiss
  Solid Freeform Fabrication: A New Direction in Manufacturing, J. Beaman, et. al, ed., Kluwer, 1997.

• Novel Applications and Implementations of Shape Deposition Manufacturing
  L. Weiss and F.B. Prinz
  Naval Research Reviews, Vol. 1, 1998.

• In Vitro analysis of biodegradable polymer blend/hydroxyapatite composites for bone tissue engineering
  K.G. Marra, J.W. Szem, P.N. Kumta, P.A. DiMilla, and L. Weiss
  J. Biomed. Mat. Res., Vol. 47, 1999, pp. 324 - 335.